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Five countries from three continents have participated in this research

A project will use gene therapy with nanoparticles to combat glioblastoma, a highly aggressive brain tumor


A project will use gene therapy with nanoparticles to combat glioblastoma, a highly aggressive brain tumor


The head of Pharmacology at the University of Castilla-La Mancha (UCLM) Valentin Ceña, the researcher in charge of the Associated Unit Neurodeath, will coordinate a multinational project which includes, both research groups from Taiwan, Canada, France, Lithuania and Spain, and a Canadian firm, in order to demonstrate the therapeutic effectiveness of gene therapy with nanoparticles for treating glioblastoma, a type of very serious brain tumor.

The research project entitled: “Nanomedicine for glioblastoma therapy”, contemplates the selective direction of small molecules named nanoparticles: "they are tiny. To give you an idea, the thickness of a human hair is equivalent to 50,000 of these small structures". These will carry inside them different therapeutic molecules for brain tumours, created in mice using tumorous cells obtained in patients diagnosed with glibostama".

"The project will study the capacity this new family of therapeutic molecules has for reducing or even eliminating the tumour implants in mice, thereby providing supporting evidence for the concept that this new therapy could be effective in treating glioblastoma", stated Valentin Ceña.

This research project was passed in the “10th Joint Transnational Call (JTC)”, within the framework of the ERA-NET EuroNanoMed III. This is a very competitive call, since out of the 91 projects initially presented, only thirteen received funding, one of which was that coordinated by professor Valentin Ceña.

"Carrying out this project will enable this university to have an international standing in research into applications for nanoparticles in cancer therapy, a leading field, which has only just begun, but which could potentially challenge various concepts that are at present accepted in the field of anti-tumour therapy", said professor Ceña.

UCLM Communication Office Albacete, 9th of October 2019

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